Krabbe+Disease

Krabbe Disease

Who is effected by Krabbe disease and how does it effect them?

Krabbe Disease effects infants when they are around the age of 3- 6 months. The chances of a person having Krabbe Disease is 1 to 100,000. Some Arab countries have chances of 1 to 6,000. People in Scandanavia have a 1 in 50,000 chance of getting Krabbe Disease. Not only are humans effected by Krabbe Disease, some dogs were found with Krabbes Disease including Westies and Carin Terriers. The Krabbe Disease effects the myelin sheath of the nervous system. The disease is only seen from birth.

What are the signs and symptoms of Krabbes Disease?

Some of the signs symptoms are...
 * Irritability
 * Fevers
 * Limb stiffness
 * seizures
 * feeding difficulties
 * vomiting
 * slow mental development
 * muscle weakness
 * spasticity
 * deafness
 * optic atrophy
 * blindness
 * paralysis

How do people get this disease?

The Krabbe Disease is a defect in The GALC system. People with this disease don't have enough galactose. We need this to make myelin Myelin is a material that surrounds and protects the muscles. Krabbe disease is inherited, which means that it runs in families. To get this disease, each of your parents must pass you a copy of the GALC gene.This disease damages the central nervous system. media type="youtube" key="PZ-X3-KeWS8" height="266" width="277"